Study the Effect of Selenium Supplementations on the Liver, Kidney and Thyroid Gland Activities in Male Rats

The liver, kidney, and thyroid glands are main vital in biochemical physiological activities animals humans. In this study, we examined the effects of adding selenium supplementation on improvement activity many such as after cadmium chloride administration (induced toxicity) male rabbits. This study included 16 rabbits divided into four groups, 1st group (CON) was control normal fed drinking water, 2nd (NC ) negative that 1ml (100ppm) with fed, 3rd (S1) sodium selenite, 4th (S2) 5ml all groups continuous for same style up to 8th week experiment. Antioxidant oxidative stress status investigated by measuring levels T-AOC MDA. liver assessed estimation ALT, AST, TP, TB while kidney calculation blood CRI UR gland measurement serum T3 T4. selenoprotein (SeP) mg/l were HPLC standard S2 group. results present shows highly statistical differences between when compare mean±SD ALT,AST,TP,TB,CRI,UR,T3, T4 (p-value <0.005). conclusion, showing ability lowering markers work protective factor from toxicity induced